Bowman Lab
Department of Biochemistry
Jacobs School of Medicine & Biomedical Sciences
University at Buffalo
Lab News!
New Paper Just Accepted!
April 2026
We have been collaborating with the Perry Lab at UMass Amherst, who have developed a microfluidic platform, LEAP-X, for macromolecular crystallization and data collection. Our paper was just accepted at Lab on a Chip!
LEAP-X is an electrically-actuated microfluidic device made of an X-ray transparent polymer. The device enables us to set up a crystallization experiment directly on the same platform on which we collect X-ray diffraction data (no crystal fishing 💎🎣 required)! Wonderful to see the LEAP-X in action for rubrerythrin, one of the metalloproteins we study in my group.
Paper: LEGO®-inspired electrically-actuated microfluidics for on-chip protein crystallization and in situ X-ray crystallography, Lab on a Chip, 2026, Advance Article
Samantha Arnone Travel Award to attend ASBMB!
March 2026
Congratulations to Samantha Arnone for being awarded a Travel Award from UB Experiential Learning Network for undergraduate research!
Sam's award helped to fund her participating at the American Society for Biochemistry and Molecular Biology Annual Meeting in National Harbor, MD in March 2026.
Congratulations Sam!
Chris Campomizzi wins ACA Awards
July 2025
Congratulations to postdoc Dr. Christopher Campomizzi, who was awarded a Travel Award to attend the 2025 ACA Annual Meeting!
Chris also received the 2025 Structural Dynamics Poster Prize during the ACA Meeting!
Double Congrats Chris!
New Publication Featured on Cover!
June 2025
New from Gabrielle Budzsizewski & Sarah Bowman, in collaboration with Vivian Stojanoff from NSLS-II!
Highlighting sample preparation parameters that should be considered prior to biomolecular crystallization experiments. Originally we presented this material in the SAMPREP (Sample Attributes for Multiple techniques and Principal Requirements for Experiments in Pan-structural biology) workshop during the 73rd Annual American Crystallographic Association Meeting in July 2023. Nice to see it in publication form!
Link to paper: Preparing for successful protein crystallization experiments
Pittsburgh Diffraction Society Travel Awards!
Oct 2024
Congratulations to Dr. Budziszewski, Tiffany Wright, and Elizabeth Snell! The Dream Team all received Travel Awards to the Pittsburgh Diffraction Conference!
They also organized and taught a hands-on workshop on crystallization as a satellite workshop to the conference.
Great work!
Dr. Bowman Elected as an ACA Fellow!
July 2024
Congratulations to Dr. Bowman for being elected in 2024 as a new Fellow of the American Crystallographic Association – the Structural Science Society.
ACA Fellows serve as scientific ambassadors to the broader scientific community and the general public to advance science education, research, knowledge, interaction, and collaboration.
New Publication: Reaching the potential of electron diffraction
June 2024
A collaborative effort between our CryoEM team Devrim Acehan and Katherine Spoth, and the nanocrystal technology development expertise from Miranda Lynch, and the Bowman Group, Gabrielle Budziszewski, PhD, Elizabeth Snell, & Chris Campomizzi, PhD.
Microcrystal electron diffraction (MicroED) is an expanding diffraction-based method making headway in both small-molecule and macromolecular structural science. The perspective discusses electron diffraction, providing an overview of current approaches and tools for implementation, as well as describing challenges and the need for technological developments going forward.
Link to paper: https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864(24)00275-3
New Publication in Acta Cryst C on electron diffraction
June 2024
Dr. Bowman was an invited speaker at a symposium at the National Center for CryoEM Access and Training housed at the New York Structural Biology Center in November 2023. The symposium participants have published an article describing cutting-edge developments in various facets of the field and identifies potential avenues for continued progress in electron diffraction.
Link to paper: https://onlinelibrary.wiley.com/iucr/doi/10.1107/S2053229624004078
